AC and DC electrospinning of hydroxypropylmethylcellulose with polyethylene oxides as secondary polymer for improved drug dissolution
نویسندگان
چکیده
منابع مشابه
A Novel Multilevel Ac–Dc-Ac Converters with Improved Efficiency
Multilevel inverter technology has emerged recently as a very important alternative in the area of high power medium-voltage control and also for improving the total harmonic distortion by reducing the harmonics. Generally, the poor quality of voltage and current of a conventional inverter fed induction machine is obtained due to the presence of harmonics and hence there is a significant level ...
متن کاملIncrease in Dissolution Rate of Simvastatin by Amorphous Solid Dispersion System with Hydroxypropylmethylcellulose Polymer
The objective of the present study was to prepare amorphous solid dispersion system simvastatin–hydroxypropylmethylcellulose (HPMC) to enhance the dissolution rate. Amorphous solid dispersion of simvastatin was prepared by solvent technique using HPMC as carrier with ratio of 1:1, 1:3 and 1:5 (w/w). Physicochemical properties of solid dispersions were investigated by X-ray powder diffraction, t...
متن کاملEntrapped chemically synthesized gold nanoparticles combined with polyethylene glycol and chloroquine diphosphate as an improved antimalarial drug
Objective(s): Drug delivery is an engineering technology to control the release and delivery of therapeutic agents to target organs, tissues, and cells. Metallic nanoparticles, such as gold nanoparticles (AuNPs) have exceptional properties which enable efficient drug transport into different cell types with reduced side effects and cytotoxicity to other tissues.Materials and Methods: AuNPs were...
متن کاملSpace-charge dynamic in polyethylene: from dc to ac stress
Time-resolved space charge profiles obtained in low density polyethylene under sinusoidal or square AC stress for frequencies going from DC to 10 Hz, temperature from 25 to 50°C and fields of 30 or 40 kV/mm are presented. It is shown that most of the features observed under DC stress (generation of carriers of the two polarities with non-symmetrical amount and velocity) are still active under A...
متن کاملEnhancing Dissolution Rate of Carbamazepine via Cogrinding with Crospovidone and Hydroxypropylmethylcellulose
Carbamazepine belongs to the class II biopharmaceutical classification system (BCS) which is characterized by a high per-oral dose, a low aqueous solubility and a high membrane permeability. The bioavailability of such a drug is limited by the dissolution rate. In order to increase the drug dissolution, its solid dispersions were prepared by the cogrinding technique using an insoluble but highl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2016
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2016.03.024